The following classes of diuretics that may result in a cross sensitivity reaction with sulfonamides is thiazides diuretics. The effects of the thiazides diuretics is to pass out fluid in the kidney.They do this by interfering with the transport of salt and water across certain cells in the kidneys. It tends to have only a week action on the kidneys and as a result the patient doesn’t notice a great increase in urine if this medicine is taken.
