Exercise-induced changes in acid-base and ion balance in normoxic and normobaric hypoxia
Complex alterations in acid-base balance are brought on by both exercise and hypoxia. The current study's goal was to determine if the modified physicochemical approach provides a better understanding of the changes in acid-base homeostasis after vigorous physical activity in normoxic and hypoxia than the conventional Henderson-Hasselbalch technique.
Methods
In this prospective, randomized, crossover trial, 19 healthy males underwent two study days of normoxia (12%) and normobaric hypoxia (12% oxygen, equivalent to an altitude of 4500 m) and exercised on a bicycle ergometer until voluntary exhaustion. Following the exercise test, arterial blood gases were sampled and analysed using the modified physicochemical approach and Henderson-Hasselbalch approach, respectively.
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