Inside an engine, gasoline combines with a spark to create combustion which in turn spins the wheels and moves the vehicle. Which parts of this process make the chemical reaction system?

Answer: the best option to answer the question is the last one ("the gasoline and spark")
Explanation:
The question requires us to choose the correct option that indicates the chemical reaction in the system given.
Considering the engine system given and the steps described, we can say that when gasoline is burned (combined with a spark to create combustion), there is a chemical reaction happening. On the other hand, the turning of the wheels and vehicle moving are not entirely chemical processes, although they are able to happen because of the energy released by the chemical reaction. These two process are mechanical as they involve the movement of the vehicle.
Therefore, the best option to answer the question is the last one ("the gasoline and spark").