What was the significance of the Treaty of Tordesillas? It gave the Catholic church the right to establish missions in the Americas. It ended the Seven Years' War between Spain and Portugal. It first granted Spain the right to lands in the Americas. It gave Portugal the chance to establish colonies in the Americas.

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In theory, the Treaty of Tordesillas divided the New World into Spanish and Portuguese spheres of influence. The treaty amended papal bulls issued by Pope Alexander VI in 1493. These declarations had granted Spain an exclusive claim to the entirety of North and South America.

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