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Which of these best explains the difference between eukaryotes and prokaryotes? Choose the correct answer. Eukaryotes have simpler cells and can only be unicellular. Eukaryotes have simpler cells and can be either unicellular or multicellular. Eukaryotes have more complicated cells and can only be multicellular. Eukaryotes have more complex cells and can be either unicellular or multicellular.