What is a prudent estimate of the population of Native Americans in North America at the time of Columbus's arrival in the New World

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Answer:

A prudent estimate would be around 7 million people in North America, less than 1 million of them in modern-day Canada, and the rest in the United States.

The least conservative estimates give North America a figure of around 12 million people. However, it still pales in comparison with in Central and South America according to most estimates (around 37 million people).